The TOXI Group is developing research in toxicology applied to human disease, environment and marine biotechnology. The group consists of 3 complementary research laboratories (Toxicology, BioTox, and SeaTox Labs).
The Toxicology Lab aims at evaluating drug safety and the development of biomarkers. A broad range methodologies are applied with a mindset towards the implementation of new advanced experimental systems and generation and interpretation of big data, in parallel to conventional toxicokinetic and toxicodinamic studies. The Adverse Outcome Pathways concept linking the biological cascade from the insult at the molecular initiating events to the adverse effects, has been enforced in practical strategies, and focused on translational outcomes.
The SeaTox Lab associates marine environment and human health. We merge Systems Toxicology, Stress Biology and Evolutionary Ecophysiology into pure and applied research related to resilience to ocean warming and other aspects of global change; monitoring carcinogens and emerging toxicants, plus the development of novel therapeutic agents from marine toxins and metabolites.
The Biotox Lab aims at developing studies on environmental toxicology (e.g. effects of nanomaterials, heavy metals, quantum dots and endocrine disruptors in organisms). We have also been studying the effects of climate change on marine biota. A recently implemented research line focuses on toxicology and food safety, namely seafood.